Anal cancer is a tumor that grows in the anus or anal canal. Infection with HPV is a major risk factor. Treatment can be effective in the early stages.4/5(). Many anal cancers are linked to lifestyle or other risk factors. Having these risk factors does not mean that you will definitely develop cancer. Nov 13, · Risk Factors for Anal Cancer; What Causes Anal Cancer? Can Anal Cancer Be Prevented? More In Anal Cancer. About .